Red mist was a substance created by the Agorians. It was contained inside a glass container. If Ratchet broke one of these containers with his Wrench he would release the mist, any Agorian who was exposed to red mist, would go berserk. Once an Agorian was exposed to the mist, it became larger in size and took a lot more firepower to defeat it.
- Ratchet & Clank Future: A Crack in Time (first appearance)